Phone: 247-5000 local 3301

Email: kadecastro@mapua.edu.ph

Honors and Awards:

• Best Thesis Adviser - Undergraduate Level, Synthesis and Characterization of Palladium Nanoparticles chelated on 2-pyridinecarboxaldehyde functionalized Cobalt ferrite silica gel support for the Reductive Hydrodechlorination of Chlorinated Organic Compounds, Mapua University, March 2018.
• Cardinal Excellence Award for h-index, 2018
• Cardinal Excellence Award for Top 10 highest h-index, 2018
• Best Thesis Adviser - Undergraduate Level, Removal of Chromium Metal from Tannery Wastewater Utilizing Al and Al-Fe Plate-shaped Electrodes and Dimethicone via Bipolar Electrocoagulation, Mapua University, March 2017.
• Dr. Ang Tiao Kim's (DATK) Outstanding Faculty Member Award, MIT-CCAA, 2016
• Best Thesis Adviser - Undergraduate Level, Hydrodechlorination of p-dichlorobenzene in Aqueous Media using Palladium Nanoparticle Immobilized on Various Resin Supports as Catalyst, Mapua Institute of Technology, May 2014.
• World Intellectual Property Office Scholarship for LL.M IP Recipient, 2012
• Mapua Institute of Technology, Dean's Council Scholarship Recipient, 2012
• Mapua Institute of Technology Top Ten Outstanding Performers in Research Publication Award Recipient, 2012
• Mapua Institute of Technology Top Ten Outstanding Performers in Research Publication Award Recipient, 2011
• Mapua Institute of Technology Top Ten Outstanding Performers in Research Publication Award Recipient, 2010
• Hanyang International Scholarship Program Recipient, 2006
• Brain Korea 21 Scholarship Recipient, 2006
• Mapua Institute of Technology, Dean's Council Scholarship Recipient, 2006
• Mapua Institute of Technology, Dean's Council Scholarship Recipient, 2004
• Dr. Ang Tiao Kim's (DATK) Outstanding Faculty Member Award, MIT-CCAA, 2002
• Dr. Ang Tiao Kim's (DATK) Outstanding Faculty Member Award, MIT-CCAA, 2001
• Gloria Mapua Lim Scholarship Recipient, 1995

• Organic and organometallic synthesis applied to several organic transformation and catalysis
• Nanomaterial synthesis for catalysis
• Natural products isolation, structure elucidation and application to medical and agricultural fields
• Wastewater treatment/remediation via electrocoagulation

Publications
Patents 

• Cruz, K. D., Paragas, D. Biocides from Botanical Extracts and Method of Preparation thereof. Application No. 1/2018/050031, 2018.
• De Castro, K. A., Rhee, H. Lim, M.-K, Lee, K. S., Chang, Y. W. Supported Catalyst Comprising Nano Palladium and Method for Preparation Thereof. KR1012489340000, 2013.
• De Castro, K. A., Rhee, H. A method for preparing Teprenone. KR1010637560000, 2011.
• De Castro, K. A., Rhee, H. Intermediate of racemic Tolterodine. KR1009263100000, 2009.
• De Castro, K. A., Rhee, H. Method of preparing racemic Tolterodine, intermediate of racemic Tolterodine, and method of preparing the same. KR1009186920000, 2009

Papers

• A. B. Alimboyoguen, K. A. De Castro-Cruz, I.A. V. Altena, C. Y. Ragasa. Triterpenes from Pittosporum resiniferum Hemsl. International Journal of Toxicological and Pharmacological Research, 2016, 8(4):261-262.
• De Castro, K. A., Thee, H. Resin-immobilized palladium nanoparticle catalysts for Suzuki-Miyaura cross-coupling reaction in aqueous media. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2015, 82(1-2), 13-24.
• A. B. Alimboyoguen, K. A. De Castro-Cruz, C.-C Shen, W.-T. Li, C. Y. Ragasa. Chemical constituents of the bark of Aleurites moluccana L. Willd. Journal of Chemical and Pharmaceutical Research, 2014, 6(5):1318-1320.
• A. B. Alimboyoguen, K. A. De Castro-Cruz, C.-C Shen, C. Y. Ragasa. Chemical Constituents of Anacolosa frutescens. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2014, 1189.
• C. Y. Ragasa, O. B. Torres, C.-C. Shen, L. O. Bernardo, E. H. Mandia, K. A. De Castro-Cruz, P.-W. Tsai. Chemical Constituents of Ficus linearifolia and Ficus triangularis. Chemistry of Natural Compound, 2014.
• P.-W. Tsai, K. A. De Castro-Cruz, C.-C. Shen, C.-T. Chiou, and C. Y. Ragasa. Chemical Constituents of the stems of Ficus trianglaris. Der Pharmacia Lettre, 2014, 6 (5):130-133
• P.-W. Tsai, K. A. De Castro-Cruz, C.-C. Shen, C.-T. Chiou, and C. Y. Ragasa. Chemical Constituents of Artocarpus camansi. Phcog. J., 2013, 5, 80-82.
• P.-W. Tsai, K. A. De Castro-Cruz, C.-C. Shen, C.-T. Chiou, and C. Y. Ragasa. Chemical Constituents of Ficus odorata. Pharm. Chem. J., 2012, 46(4), 225-227.
• Tsai Po-wei, De Castro-Cruz Kathlia A, Shen Chien-Chang and Ragasa Consolacion Y. Chemical constituents of Broussonetia luzonicus. Phcog J. 2012, 4(31), 1-4.
• Lim, M., De Castro, K. A., Oh, S., Lee, K., Chang, Y.-W., Kim, H., Rhee, H. Palladium nanoparticles dispersed on solid supports:synthesis, characterization and catalytic activity on selective hydrogenation of olefins in aqueous media. Appd. Organomet. Chem. 2011, 25, 1-8.
• Park, J. M., De Castro, K. A., Ahn, H., Rhee, H.  Facile Synthesis of L-α-glycerophosphorylcholine. Bull. Korean Chem. Soc. 2010, 31, 2689-2691.
• Cho, D., Ahn, J., De Castro, K. A., Ahn, H., Rhee, H. P₄S₁₀/dimethicone tandem: efficient reagent for thionation of various aromatic amides and esters. Tetrahedron 2010, 5583-5588.
• An, G., Ahn. H. De Castro, K. A., Rhee, H. Pd/C and NaBH₄ in Basic Aqueous Alcohol: An Efficient System for an Environmentally Benign Oxidation of Alcohols. Synthesis 2010, 477-485.
• De Castro, K.A., Byun, E. Y., Rhee, H. Diketene and Acetylated Meldrum’s Acid: Agents for a Facile Teprenone Synthesis via Carroll Rearrangement. Bull. Korean Chem. Soc. 2009, 30, 2155-2157.
• De Castro, K.A., Oh, S., Yun, J., Lim, J. K., An, G., Kim, D. K., Rhee, H. Colloidal Palladium Nanoparticles with In Situ H₂: Reducing System for Unsaturated Carbonyl Compounds. Synth. Commun. 2009, 39, 3509-3520.
• De Castro, K. A., Rhee, H. Selective Nosylation of 1-Phenylpropane-1,3-diol and Perchloric Acid Mediated Friedel–Crafts Alkylation: Key Steps for the New and Straightforward Synthesis of Tolterodine. Synthesis, 2008, 1841–1844.
• Byun, E., Hong, B., De Castro, K. A., Lim, M., Rhee, H. One-Pot Reductive Mono-N-alkylation of Aniline and Nitroarene Derivatives Using Aldehydes. J. Org. Chem. 2007, 72, 9815-9817.
• Ahn, H., Choi, T. H. De Castro, K. A., Lee, K. C., Kim, B., Moon, B. S., Hong, S. H., Lee, J. C., Chun, K. S., Cheon, G. J., Lim, S. M., An, G., Rhee, H.              Synthesis and Evaluation of cis-1-[4-(Hydroxymethyl)-2-cyclopenten-1-yl]-5-[¹²⁴I]iodouracil: A New Potential PET Imaging Agent for HSV1-tk Expression. J. Med. Chem. 2007, 50, 6032-6038.
• De Castro, K. A., Ko, J., Park, D., Park, S. Rhee, H. Reduction of Ethyl Benzoylacetate and Selective Protection of 2-(3-Hydroxy-1-phenylpropyl)-4-methylphenol: A New and Facile Synthesis of Tolterodine. Org. Proc. Res. Dev. 2007, 11, 918–921.